Permanent Position: Full Time. Part-Time and Flexible working considered
Flexible location: Can be homebased. Willingness to travel, as needed, within the UK (Nottingham, Sheffield, London) for team meetings and study participant testing
Compensation: Industry competitive compensation (payroll +Pension +Bonus)
Why Rinri Therapeutics?
Rinri Therapeutics is a cutting-edge biotechnology company based in Sheffield (UK) dedicated to developing a completely new cell therapy paradigm to treat hearing loss. Our science originates from the world-renowned Stem Cell Institute at the University of Sheffield and the world-leading
research from Professor Marcelo Rivolta on pluripotent and progenitor cells (see Chen et al., 2012 doi: 10.1038/nature11415). Since our inception in late-2018, we have established a world-class team, including Chief Medical Officer, Professor Doug Hartley, to realise the vision of meeting unmet patient and clinical needs in hearing loss and improving patients’ quality of life on a global scale.
What do we want?
Rinri has a small, ambitious, and multi-skilled entrepreneurial team with extensive scientific, clinical, operational and commercial experience. This role would sit within the Clinical Development and Operations Team who are currently working closely together on the set up of the first in human trial of our lead product, the world’s first regenerative cell therapy for hearing loss. Our clinical development colleagues work side by side with clinical operations to ensure these needed treatments are brought to patients as quickly as possible, on the foundations of the most robust science and outcomes.
We invite applications from a wide range of specialties (academic and clinical) who could translate their unique skillset across our portfolio of clinical development work. We are looking for a dynamic individual who will initially support their colleagues in clinical development studies and activities associated with the trial set-up. Going forward, the role holder would be expected to use the full breadth of their research skills, using qualitative and quantitative methods, to contribute towards the clinical development strategy underpinning the ongoing development of our lead product, and other cell therapy products in our pipeline. This work will include international collaboration, literature reviews, planning and hands on designing and running of studies with research participants. Areas of research could be varied, including epidemiology studies, clinical outcomes development, audiological diagnostics, speech testing, imaging, clinical trials methodology and patient and public engagement. This role will report to the Vice President of Clinical Development.
We are offering the opportunity to a talented and motivated scientist, looking to develop a multi-disciplinary and exciting career within a truly pioneering UK biotechnology company looking to
realise the long-promised potential of cell therapy to improve patients’ lives
Responsibilities (to include but not limited to):
Contributing to the design, planning and implementation of translational research studies:
- Support the development of proposals for future studies including contributing to applications for external funding, as required
- Literature Reviews
- Collaborative protocol development and submission of applications for ethical and other local approvals for clinical development studies
- Working with clinical operations colleagues to develop aspects of essential documents, study plans and training materials for clinical trials
- Recruit and arrange testing with research participants of clinical development studies
- Ensure conduct of research according to required regulations and ensure maintenance of accurate records, according to data protection guidelines
- Ensuring clinical development projects are delivered on time and keeping colleagues and stakeholders up to date with timelines
- Proactive identification of potential project issues and risks
- Keep abreast of the relevant literature and critically review the literature relating to the research area
- Provision of regular and ad-hoc information and updates, both written and verbal, to internal team (VP, CMO, CEO)
- Building close internal and external relationships (clinical and academic experts in the field) in order to exchange information, facilitate collaboration, and identify potential areas for further clinical development
- Coordinate internal and external meetings with stakeholders and collaborators
- Prepare and deliver oral presentations and posters for academic and clinical conferences
- Publish in appropriate peer-reviewed academic journals commensurate with the stage of career
- Contribute to activities to raise public and professional awareness of Rinri
- Any other duties as assigned
Required Experience and Skills:
- PhD in a Relevant Scientific Discipline, or advanced degree and significant research experience. Relevant Disciplines may include, but are not limited to: Audiology, Neurosciences, Speech and Language Therapy, Clinical Research
- Demonstrable experience in translational research
- Excellent oral and written communication skills, including the ability to communicate with clarity on complex information.
- Ability to build relationships and collaborate with others at all levels of seniority, both internally and externally in order to deliver objectives
- High analytical ability to analyse and illuminate data, interprets reports, evaluate and criticise texts and bring new insights.
- Ability to creatively apply relevant research approaches, models, techniques and methods.
- Good analytical and organisational skills, attention to detail and lateral thinking
- High degree of motivation, problem solving skills and innovative thinking.
- Comfortable in a dynamic small company environment and able to adjust workload and responsibilities based on changing priorities
- Excellent working knowledge of relevant IT operating systems and software packages
- Statistical knowledge sufficient to analyse data generated and present in a report
- Experience of applying for research ethics
- Understanding of the life cycle of clinical trials
- Experience of developing new approaches, models, techniques, or methods in research area
- Knowledge of programming, both statistical and general (e.g. MATLAB, Python)
- Track record of high-quality publications
- Specialist knowledge in hearing loss, audiology and/or otology
Deadline: Application will be considered on a rolling basis, and no further applications will be accepted after 3rd January 2024.
Application Requirements: Please send a CV and detailed cover letter specifically addressing why you would be a good addition to the Clinical Development Team at Rinri to: email@example.com
Contact: Questions may be addressed to the Vice President of Clinical Development, Rachel Haines, on the above email address